2024 - Biennial Meeting of the Neurotoxicity Society
Mercure Hotel Rio Vermelho
Salvador Bahia Brazil
SCIENTIFIC PROGRAM
Opening Lecture: ● Rita Raisman-Vozari (Paris Brain Institute, University of
Sorbonne, France) - How serendipity remains a powerful tool in the discovery of
neuroprotective drugs.
Tribute to Arne Schousboe - Marta Antonelli
Symposium I –Mechanisms on Neurotoxicity I. Chair: Marta Antonelli
● Thaís Antonia Alves Fernandes (University of São Paulo-RP, Brazil) - Neuroprotective
effect against aggregation of phosphorylated tau protein from non-antibiotic
tetracyclines derivatives in primary culture of cortical neurons
● Jordi Duran (University of Chile, Chile) – Glycogen-induced neurotoxicity.
● Marta Antonelli (University of Buenos Aires, Argentina) -Longitudinal study of the effect
of gestational stress on the newborn and its subsequent neurodevelopment.
Symposium II – Mechanisms on Neurotoxicity II. Chair: Pablo Caviedes
● Karen Renata Herculano Matos Oliveira (Federal University of Pará, Brazil) -
Neurocognitive impacts of severe malaria: mechanism of action and preclinical
evaluation of bioactive compounds.
● Andrea Paula Lima (University of Chile, Chile) - Role of endoplasmic reticulum-mediated
calcium signaling in the toxicity of Alzheimer's disease-related amyloid-beta peptide
oligomers.10
● Pablo Caviedes (University of Chile, Chile) - P21 Activated kinase (PAK) as a
therapeutical target in Down syndrome neuronal dysfunction: Effect on cell process
formation and emission.
● Patrícia Fernanda Schuck (Federal University of Rio de Janeiro, Brazil) – Galactose
neurotoxicity in galactosemia experimental models.
10/09/2024
Symposium III –Neurotoxicity and Neuroprotection I. Chair: Gustavo Ferreira
● Francisco Guimarães (University of São Paulo-RP, Brazil) – Cannabidiol in Psychosis.
● Glauce Crivelaro do Nascimento (University of São Paulo, Brazil) – Anti-nociceptive
effects of non-antibiotic derivatives of demeclocycline and doxycycline against formalin-
induced pain stimulation.
● Gustavo Ferreira (Federal University of Rio de Janeiro, Brazil) – “Not so” neuroprotective
effect of carnosine.
Symposium IV – Neurotoxicity and Neuroprotection II. Chair: Victor Diogenes
A.l da Silva
● Andrea Paula Lima (University of Chile, Chile) - The detrimental role of calcium signaling
in Alzheimer’ disease amyloid pathology.
● Henning Ulrich (University of São Paulo, Brazil) - Purinergic signaling in neurotoxin-
induced dopaminergic degeneration.
● Victor Diogenes (Federal University of Bahia, Brazil) - Molecular mechanisms in
Parkinson’s disease and potential use of flavonoid rutin.
Symposium V- Control of Neuroinflammation in Brain Diseases - Chair: Elaine
Del Bel
● Bianca Andretto de Mattos (University of São Paulo-RP, Brazil) - The physiological
antioxidant uric acid and the non-antibiotic derivative of oxytetracycline, DOT, reduce
pathological tau abnormalities induced by low-level oxidative injuries.
● Rommy Von Bernhardi Montgomery (University San Sebastian, Chile) - Microglial cell11
regulation changes in aging and neurodegenerative disease.
● Alexandre Amaral (University of Rio Grande do Sul, Brazil) - Protective role of PPAR
activation on D-2-hydroxyglutaric acid neurotoxicity in vivo.
● Elaine Del-Bel (University of São Paulo-RP, Brazil) - Cannabidiol and Cannabigerol limit
L-DOPA-induced dyskinesia when given separately or in combination to
hemiparkinsonian rats.
Poster Session
11/09/2024
Symposium VI -Neuron glia interaction in health and disease. Chair: Silvia Costa
● Silvia Oliveira Bravo (Biological Research Institute Clemente Estable, Uruguay) Synthetic
chalcones to prevent white matter disease.
● Patricia Cassina (University de la Republica, Uruguay) - Glial reactivity and mitochondrial
modulation in chronic pain.
● Coral Sanfeliu (Institute of Biomedical Research of Barcelona, Spain) - High prenatal
levels of epoxyeicosatrienoic acids protect against developmental neurotoxicity and
neurodegenerative injuries.
Closing Conference: Moacir Wajner (Federal University of Rio Grande do Sul,
Brazil) - Organic acid neurotoxicity and the pathogenesis of organic acidemias.
Meeting program
Neurotoxicity Society Virtual Meeting 2021
June 17-18
Day 1
Welcome (NTS President and Program Committee)
Session I:
MPTP intoxication in the Octodon degus: effects on the nigrostriatal pathway and related areas.
Lorena Cuenca-Bermejo (Mentor: Maria Trinidad Herrero)
Early changes in epigenetics and oxidative stress in Old Parkinsonian mice.
Pablo Gallo-Soljancic. (Mentor: Maria Trinidad Herrero)
Study of the anti-inflammatory and neuroprotective effect of flavonoid rutin in a pre-clinical model of Parkinson’s disease induced by aminochrome.
Fillipe Mendes De Araújo (Mentor: Victor Diogenes Amaral Silva)
Discussion (Chair: María Trinidad Herrero)
Cannabidiol attenuates non-motor symptoms in parkinsonian rats.
Bianca Andretto de Mattos (Mentor: Maria M. Weffort de Oliveira)
Effects of ethyl-acetate fraction of Trichilia catigua on memory and oxidative stress after cerebral ischemia: An analysis of the time window of efficacy.
Daniela Velasquez de Oliveira (Mentor: Humberto Milani)
Discussion (Chair: Harry Steinbusch)
Session II
Different short-predictable stress in juvenile rats have no long-lasting effects on the volume of corpus callosum, hippocampus neither anxiety-like behavior or object recognition memory.
Lucas Brunati Gremaschi. (Mentor: Silvana Regina de Melo)
ALDH2 inhibition by Lead and Ethanol co-exposure: impact on bioenergetics and oxidative stress biomarkers in SH-SY5Y cells.
Romina Deza-Ponzio (Mentor: Miriam B. Virgolini)
Changes of plasma PACAP-38 level in patients with Parkinson’s disease .
Daniel Pham (Mentor: Andrea Tamas)
Modeling Parkinson´s Disease with AAV viral particles and human PFFs of α-Syn .
Mónica Gómez-Benito (Mentor: Rosario Moratalla)
Discussion (Chair: Elaine del Bel)
Day 2
Session III:
Increased expression of DSCAM and its action on neuronal morphological parameters in immortalized cell models of Down Syndrome. Possible role of the PAK effector pathway.
Ramón Pérez-Núñez (Mentor: Pablo Caviedes)
Evaluation of the impact of amyloid precursor protein (APP) and P21-activated kinase (PAK) on the morphological parameters in murine trisomy 16 neuronal cell lines, an animal model of Down syndrome.
Natalia Barraza (Mentor: Pablo Caviedes)
Neuron glial antigen 2 in the striatum of parkinsonian rats presenting L-DOPA induced dyskinesia.
Nascimento G.C (Mentor: Elaine Del-Bel).
LPS-Induced Inflammatory Reaction In Microglial Cells Is Prevented By Cannabidiol Through A Glucose Uptake-Dependent Oxidative Stress Mechanism.
Maurício Dos-Santos-Pereira (Mentor: Elaine Del Bel)
Discussion (Chair: Pablo Caviedes)
Open debate about neurotoxicity and current strategies
